Studies using the MOZART System

2017. Kaufman et al.  Poster. View for View, 3-D Specimen Tomosynthesis Provides More Data Than 2-D Specimen Mammography. Conclusion:  Use of specimen tomosynthesis in the operating room has improved the accuracy of intraoperative imaging in 43% of cases.  Link

2018.  Kornfield et al.  Publication.  Examination of time and financial savings gained by using Mozart intraoperatively compared to transporting wire guided lumpectomy specimens to radiology for examination.  Conclusions:  Use of Mozart for intraoperative imaging saved on average 7.6 minutes of OR time and $284 charge saving per patient.  Link

2019.  Park et al.  Publication.  Retrospective study of 98 lumpectomy specimens comparing institutional Standard Extensive Processing by pathology and radiology with review of Mozart images by radiology.  Conclusions:  Mozart accurately identifies SM specimens having tumor at ink, with a similar sensitivity and higher specificity compared with our institutional SEP.  Link

2020.  Munding et al.  Poster. Implementation of Intra-Operative Specimen Tomosynthesis and Impact of Re-Excision Rates for Image Guided Partial Mastectomies.  Conclusions: Use of Mozart for localization versus remote radiologic interpretation for determining additional shave margins is associated with lower positive margins rates and was shown to discover positive margins that would have been missed based on final pathology of initial specimen alone.  Link

2020.  Partain et al.  Publication. Retrospective study of 657 lumpectomy patients split into two streams.  One stream used Hologic Trident for Intraoperative imaging, the other used Kubtec Mozart.  Conclusions:   A (50%) lower re-excision rate (from 11% to 5%) is independently associated with 3D tomosynthesis. This allows surgeons to excise additional margins at the index operation, decreasing reoperations and anxiety/costs for patients.   Link

2022.  Mondani et al.  Poster SABCS.  Retrospective study of 660 lumpectomy patients split into two streams.  One stream used 2D imaging for intraoperative imaging, the other used Kubtec Mozart.  Conclusions:  The 2D cohort had a re-excision rate of 15% compared to 9% for the Mozart cohort.  Link

2023.  Manhoobi et al.  Publication.  Retrospective study of 250 lumpectomies split into two streams one using 2D introperative specimen imaging and one usineg Kubtec Mozart.  Conclusion:  No statistical differences were seen in re-excision rates between the 2D stream (19.7%) and the Mozart stream (16.8%).  Link

2024. Sinha et al.  Poster ABS (UK).  Retrospective review of lumpectomy specimen images over two year period with and without Mozart 3D imaging.  Conclusion:  Use of Mozart by a radiologist or a surgeon reduces reoperation rates for lumpectomy patients by up to 50%.  Link