Clinical Data

The XPERT 80 and XPERT 80-L by KUBTEC are self-contained X-ray imaging systems for surgical pathology specimens. The XPERT 80 system provides a large 23 x 29 cm detector and is not limited to breast specimens, including paraffin blocks, bone, etc.

The use of intraoperative 3D specimen X-ray reduced the relative risk of re-excision rate by 41% (P=0.01) without any negative impact on other parameters.

To obtain the so-called three-dimensional view (3-D), routine use of two orthogonal images have been utilized as a 3-D view. Yet in screening mammography, true 3-D mammography has now arrived as tomosynthesis, not simply two orthogonal MLO and CC views of the breast.

Image guided localization is a valuable tool commonly utilized during partial mastectomy (PM) to ensure accurate removal of early-stage breast cancer. Many techniques and imaging modalities exist to confirm completeness of the initial procedure including: six (6) quadrant shaves, selective shaves, pathologic gross evaluation and margin probe use. Still, approximately 1 out of 5 patients require a second procedure in order to obtain a negative surgical margin.

Re-excision rates using both modalities are low. A lower re-excision rate is independently associated with 3D tomosynthesis. This allows surgeons to excise additional margins at the index operation, decreasing reoperations and anxiety/costs for patients.

Intraoperative margin assessment for breast cancer patients undergoing segmental mastectomy (SM) enables identification of positive margins, with immediate excision of additional tissue to obtain negative margins.